Choosing the right database for financial and mission-critical .NET applications isn’t just about performance — it’s about security, compliance, and future-proofing your architecture. In this in-depth guide, we analyze the top 20 databases tailored for .NET developers working in high-stakes environments like banking, trading, and enterprise finance. Discover why relational databases like SQL Server and PostgreSQL dominate core transactions, how NoSQL solutions like MongoDB and Cassandra handle scalability, and why emerging technologies like QLDB and CockroachDB are reshaping auditability and global consistency. We’ll also explore critical factors like ACID compliance, real-time analytics, regulatory requirements (GDPR, PCI-DSS), and multi-region resilience — ensuring your financial systems remain robust, compliant, and ahead of evolving tech trends. Whether you’re building a high-frequency trading platform, a fraud detection system, or a next-gen banking app, this breakdown will help you select the best database — not just for today, but for the next decade.

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